Assist. Prof. Dr. Andrej Trampuz
Andrej Trampuz, MD, is a specialist of Infectious Diseases, Clinical Consultant and Head of the Infectious Diseases Research Laboratory at the Charité – University Medicine in Berlin, Germany.
Andrej Trampuz received his MD degree from the University of Ljubljana, Slovenia, in 1994, followed by specialist degrees at the internal medicine board in 1997 and at the infectious diseases board in 2001. He completed his postdoctoral research fellowship at the Mayo Clinic in Rochester, Minnesota, USA in 2001-2004, where he established the sonication procedure of removed implants. Thereafter, he established a research group at the University Hospital Basel, Switzerland, relocated to the University Hospital Lausanne, Switzerland in 2009 and was appointed as Head of the interdisciplinary Center for Septic Surgery in 2013 at the Charité – University Medicine Berlin in Germany. His laboratory research involves the development and validation of novel methods for diagnosis and treatment of implant-associated infections, including animal models, the emergence of antimicrobial resistance and the development of new diagnostic methods. He is principal investigator of clinical trials involving implant-associated infections. He authored 112 peer-reviewed publications and 6 book chapters related to biofilm, implant infection, microcalorimetry, sonication and rapid microbiological diagnosis.
In 2013, Andrej Trampuz founded the PRO-IMPLANT Foundation, dedicated to supporting research, education and management of implant-associated infections. Together with surgeons he organizes interdisciplinary Workshops on Prosthetic Joint Infection (PJI). In addition, the Charité hospital offers clinical observerships for osteoarticular infections as the Collaborative Centre of the European Society for Clinical Microbiology and Infectious Diseases (ESCMID).
Martin McNally MB BCh MD FRCSEd FRCS (Orth)
Martin McNally is the Lead Surgeon in the Oxford Bone Infection Unit at the Nuffield Orthopaedic Centre, Oxford University Hospitals, UK and Honorary Senior Clinical Lecturer at Oxford University. He spends almost all of his time in infection management. He was trained in Northern Ireland, USA and Oxford. He has a particular interest in bone reconstruction in osteomyelitis, infected fractures and non-unions. He runs research projects in outcome of treatments for bone infection and local antibiotic delivery systems. He has published over 100 peer-reviewed papers, reviews and book chapters and contributes regularly to instructional courses and international meetings on bone infection and limb reconstruction. He is President of the European Bone and Joint Infection Society and Honorary Secretary of the Girdlestone Orthopaedic Society.
McNally MA, Ferguson JY, Lau ACK, Diefenbeck M, Scarborough M, Ramsden AJ, Atkins BL. Single-stage treatment of chronic osteomyelitis with a new absorbable, gentamicin-loaded, calcium sulphate/hydroxyapatite biocomposite. Bone Joint J 2016; 98-B: 1289-1296.
Morgenstern M, Athanasou NA, Ferguson JY, Metsemakers W-J, Atkins BL, McNally MA. The value of quantitative histology in the diagnosis of fracture-related infection. Bone Joint J 2018; 100-B: 7, 966-972.
Ferguson J, Diefenbeck M, McNally M. Ceramic biocomposites as biodegradable antibiotic carriers in the treatment of bone infections. J Bone Joint Infect 2017; 2: 41-54.
McNally M, Ferguson J, Kugan R, Stubbs D. Ilizarov treatment protocols in the management of infected non-union of the tibia. J Orthop Trauma 2017; 31: S47-54.
Prof. Dr. Werner Zimmerli
Werner Zimmerli studied medicine in Basel University, Switzerland, and obtained the PhD in 1974. After continuous education in inner medicine and rheumatology, he worked in a research project at the Department of Infectious Diseases in Geneva. The project aimed to explain high susceptibility to infection of implants lead by the pathogen mechanisms. Afterwards he worked as a chief and consulting physician in Infectious Diseases department in University Hospital Basel. This was followed by examination of function of granulocytes (tutored by John Gallin) during his research stay at the National Institutes of Health in Bethesda/USA. In 1989 he completed his habilitation in internal medicine and became a professor at the University of Basel in 1992. From 1991 till 1999 he led the newly established department of Infectious Diseases at the University Hospital Basel. In 1999 he began to work as a professor and a chief physician in inner medicine at Medical University Clinic Liestal.
Since 1979 his research focus was pathophysiology and treatment of implant infections. A major breakthrough in the treatment of such infections was the proof of the effectiveness of rifampicin against biofilm infections. Together with Peter Ochsner, an orthopedic surgeon, who worked in the same hospital in the field of orthopedic infections, and infectious diseases specialist Andrej Trampuz, he developed a treatment algorithm for patients with periprosthetic infections, which was published in N Engl J Med. Werner Zimmerli was a member of Infectious Diseases Society of America (IDSA), which published guidelines for diagnosis and treatment of prosthetic infections. The guidelines are based on published therapy algorithm and apply today as an international standard.
Since his retirement as chief medical doctor, Werner Zimmerli continues to work as a consultant professor in orthopedic infections at the Medical University Clinic Liestal.
Assist. Prof. Dr. Rihard Trebše, PhD
Rihard Trebše MD PhD, obtained his medical education at Medical University in Ljubljana, Slovenia in 1993. He defended his Ph.D. thesis at Medical University in Ljubljana under the mentorship of Prof V. Smrkolj. In 2014 has been elected as Assistant Professor for Orthopaedics at Medical University in Ljubljana. Since 2012 he works as a Head of Service for Bone Infections at Valdoltra Orthopaedic Hospital, Slovenia.
Rihard Trebše is also a deputy director of Valdoltra Orthopaedic Hospital. Between 2012 and 2015 he was the president of Slovenian Orthopedic Society, since 2009 he is a national delegate from Slovenia in European Hip Society, and since 2014 he is a national delegate from Slovenia in EFORT. His surgical expertise covers: bone infection surgeries, revision and primary hip and knee arthroplasty, osteotomies around the hip and open elbow surgeries.
Assist. Prof. Rihard Trebše, MD, PhD is a renowned scientist with various research interests. His most important research field has been the treatment of prosthetic joint infections but he was also involved in hip tribology and artificial joint survivorship studies. He is involved in design of new revision implants for acetabular reconstruction. Another focus of his work is the development and evaluation of computer aided surgical techniques for joint replacement and bone osteotomies of hip and knee joint. Since late nineties his main contribution has been in implementation of CAD – CAM technologies in orthopaedic surgeries particularly in precision osteotomy cuts and socket navigation in hip replacement. He has also been investigating the importance of synovial cytology, the role of synovial interleukin, and the significance of molecular methods in diagnosing PJI.
Prof. Dr. Olivier Borens
Olivier Borens, MD, is Head of the Department of Septic Surgery and Head of the Orthopaedic-Trauma Unit of the Department for the Musculoskeletal System of the University Hospital in Lausanne (Switzerland). He has received his medical education at the University of Bâle and specialized in orthopaedics and traumatology at the hospitals of Liestal and Lausanne. After a one-year fellowship at the Hospital for Special Surgery in New York his work concentrated on the traumatology of the acetabulum and the pelvis and on infections of the musculoskeletal system, especially following joint replacement
He has made his department a reference center for orthopaedic infections of the European Society for Clinical Microbiology and Infectious Diseases (ESCMID), welcoming visitors from Europe, North and South America as well as Australia. Olivier Borens is intensely involved in scientific activities and regularly invited to present at national and international conferences. His research focuses, among others, on the prevention, diagnosis and treatment of periprosthetic infections, biofilm, local antibiotics and minimally invasive techniques in traumatology.
He is member of the European Trauma Society (ETS) and of the Swiss AO Trauma Committee as well as Board member of the European Bone and Joint Infection Society. He takes active part in the education of medical students and the training of under- and post-graduate physicians. His publication list includes more than 60 journal articles, several book chapters and a great number of abstracts.
Assist. Prof. Dr. Christian Kleber
University Center for Orthopedic- and Trauma Surgery at Carl Gustav Carus University Hospital Dresden, Germany
Prim. Priv. Doz. Dr. Bernd Preininger
Bernd Preininger is an Austrian orthopedic surgeon who received his medical diploma at the University of Vienna. He started his professional education at the Vienna Military Hospital and in Villach where he was approved as general physician. He then further specialized on muscular skeletal surgery in Villach at the Dept. of Trauma Surgery. In 2008 he went to the Center of Musculoskeletal Surgery to Berlin where he completed his residency (Prof. Haas, Prof. Perka). As a Consultant and specialist for hip and knee prosthesis, especially for revision surgery Dr. Preininger could gain a lot of experience with complex cases. After two years in a private clinic in Bavaria where Preininger was specialized on Knee arthroplasty Dr. Preininger was called to Villach again where he now is the Head of the Orthopedic Department.
During the time in Berlin Preininger closely worked together with the team of Andrej Trampuz and thereby could develop quite some expertise in treating complex infectious cases with the specialized team there. His surgical expertise now covers all of the primary and revision arthroplasty, complex osteotomies of the leg and the foot, as well as arthroscopic interventions of the knee and the foot.
Preininger has been intensively involved in the science of bone healing as well as the optimization of knee and hip arthroplasty in primary and revision situations. Preininger is a part of the PJI workshop team for already several years and enjoys in taking over responsibility for the professional education of colleges.
Dr. Petra Izakovičová